I run this same setup and like it too. When I upgraded to Ishocks that increase travel then you will get some rubbing on the inside wheel well and on the bed latch. If you bottom hard, it can force the bed open. I was able to increase the preload on my shocks and minimize this.I ran 27" Mudlite XTR's on stock suspension for awhile. They rubbed a little bit on the rear fender, front lower black piece, when jumping. Turning wasn't a problem, front tires were 27-9R-14, rears were 27-11R-14. They worked great in all types of terrain. They took away a bit of acceleration as far as power loss is concerned.
I plan on going to 26" tires next time around. I run 25" in the sand and never bottom.